Signal scan
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[edit] Signal scan - Quick Links
| Signal Scan | Predict Protein | |
| TargetP | Signal search analysis server | |
| SMART | Cleavage Site Prediction | |
| iPSORT | PSORT-B | |
| Pol3Scan | SignalP 3.0 Server | |
| ChloroP 1.1 Prediction Server |
[edit] Signal scan - Web Resources
Signal Scan
Find and list homologies of published signal sequences with the input DNA sequence.
Predict Protein
Submits your protein sequences to a suite of tools carrying out prediction of secondary structure, transmembrane regions, threading, homology modelling and signal prediction.
TargetP TargetP predicts the subcellular location of eukaryotic protein sequences.
Signal search analysis server
Signal search analysis is a general method to discover and characterize sequence motifs that are positionally correlated with a functional site. The signal search analysis server provides access to four different computer programs as well as to a large number of precompiled functional site collections. The programs offered allow: (i) the identification of non-random sequence regions under evolutionary constraint; (ii) the detection of consensus sequence-based motifs that are over- or under-represented at a particular distance from a functional site; (iii) the analysis of the positional distribution of a consensus sequence- or weight matrix-based sequence motif around a functional site; and (iv) the optimization of a weight matrix description of a locally over-represented sequence motif.
SMART
Simple Modular Architecture Research Tool: Identification of signaling domains.
Cleavage Site Prediction
Method based on an Artifical Neural Network that was learned on human secretory cleavage sites. Sequences used for network training were checked for experimental confirmation.
iPSORT
iPSORT is a subcellular localization site predictor for N-terminal sorting signals. Given a protein sequence , it will predict whether it contains a Signal Peptide (SP), Mitochondrial Targeting Peptide (mTP), or Chloroplast Transit Peptide (cTP).
PSORT-B
Protein subcellular localization prediction for Gram-negative bacteria. PSORT-B examines a given protein sequence for amino acid composition, similarity to proteins of known localization, presence of a signal peptide, transmembrane alpha-helices and motifs corresponding to specific localizations. A probabilistic method integrates these analyses, returning a list of five possible localization sites with associated probability scores. PSORT-B, designed to favor high precision (specificity) over high recall (sensitivity), attained an overall precision of 97% and recall of 75% in 5-fold cross-validation tests, using a dataset we developed of 1443 proteins of experimentally known localization.
Pol3Scan
Pol3scan recognizes the eukaryotic internal control regions A box and B box that are typical of tRNA genes and tDNA-derived elements.
SignalP 3.0 Server SignalP 3.0 server predicts the presence and location of signal peptide cleavage sites in amino acid sequences from different organisms: Gram-positive prokaryotes, Gram-negative ...
ChloroP 1.1 Prediction Server
Predicts the presence of chloroplast transit peptides (cTP) in protein sequences and the location of potential cTP cleavage sites.
